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  Indian J Med Microbiol
 

Figure 4: Photomicrographs of pancreatic tissues at 100× (upper panel) and 400× (lower panel) magnification. (A) Normal architecture of islet nest (black arrows) is observed in the normal control group. (B) The hyperglycemic group shows reduced nest of islets cells with an area of extensive fibrosis (black arrows). (C) The normal group that received 400 mg/kg of Mirabilis jalapa extract shows a normal architecture of islet nest. The black arrows indicate a normal islet cell population within several islet nests. (D) The hyperglycemic group treated with 200 mg/kg of Mirabilis jalapa extract shows mild regeneration of islet cells. The arrows indicate sparsely populated islet cells within the nest. (E) The hyperglycemic group treated with 400 mg/kg of Mirabilis jalapa extract has moderately dispersed islet nests (black arrow) when being viewed under 100× magnification.

Figure 4: Photomicrographs of pancreatic tissues at 100× (upper panel) and 400× (lower panel) magnification. (A) Normal architecture of islet nest (black arrows) is observed in the normal control group. (B) The hyperglycemic group shows reduced nest of islets cells with an area of extensive fibrosis (black arrows). (C) The normal group that received 400 mg/kg of <i>Mirabilis jalapa</i> extract shows a normal architecture of islet nest. The black arrows indicate a normal islet cell population within several islet nests. (D) The hyperglycemic group treated with 200 mg/kg of <i>Mirabilis jalapa</i> extract shows mild regeneration of islet cells. The arrows indicate sparsely populated islet cells within the nest. (E) The hyperglycemic group treated with 400 mg/kg of <i>Mirabilis jalapa</i> extract has moderately dispersed islet nests (black arrow) when being viewed under 100× magnification.