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Figure 2: Renal histopathological changes and injury scores. HE-staining of the (A) cortical and (B) medullary regions of the kidney (40×). Renal injury scores in the (C) cortical and (D) medullary regions. Sivelestat: PQ+sivelestat group; AH2QDS: PQ+anthrahydroquinone-2,6-disulfonate (AH2QDS) group. Compared to the control group, **P<0.01; Compared with the PQ group, #P<0.05, ##P<0.01. Yellow arrows indicate red stain deposition, green arrows indicate hemorrhage and congestion, blue arrows indicate cavitation degeneration, and black arrows indicate casts. |
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