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  Indian J Med Microbiol
 

Figure 2: (A) Time kill curves of A. fumigatus after treatment with AMB, CG, and CG/AMB; (B) Effect of CG and/or AMB on fungal load in lung homogenate; (C) Effect of CG and/or AMB on lung gliotoxin concentration. IPA: invasive pulmonary aspergillosis. Data are expressed as means ± SD. Bars with different letters show statistically significant differences between the groups (P<0.05); (D) SEM of A. fumigatus treated with saline (a and b) or CG/AMB (c, d). Scale ba: 100 nm. (a,b) Hyphae are elongated and infrequently branched. The surfaces of the hyphae are smooth. (c) An atrophied hyphal tip is displayed separately. The branched hypha (arrowheads) has been destroyed beyond recognition. The hyphal surface is rough. Clear bumps seen at the tip (arrow) cannot be specified and are either abnormally shaped cell walls or attachments of some unknown material. (d) Typical swollen cell visible at the hyphal tip. The neck of the swollen cell has become thin and the hyphal surface is smooth. Magnification 100×. Scale bar: 100 nm.

Figure 2: (A) Time kill curves of <i>A. fumigatus</i> after treatment with AMB, CG, and CG/AMB; (B) Effect of CG and/or AMB on fungal load in lung homogenate; (C) Effect of CG and/or AMB on lung gliotoxin concentration. IPA: invasive pulmonary aspergillosis. Data are expressed as means ± SD. Bars with different letters show statistically significant differences between the groups (P<0.05); (D) SEM of <i>A. fumigatus</i> treated with saline (a and b) or CG/AMB (c, d). Scale ba: 100 nm. (a,b) Hyphae are elongated and infrequently branched. The surfaces of the hyphae are smooth. (c) An atrophied hyphal tip is displayed separately. The branched hypha (arrowheads) has been destroyed beyond recognition. The hyphal surface is rough. Clear bumps seen at the tip (arrow) cannot be specified and are either abnormally shaped cell walls or attachments of some unknown material. (d) Typical swollen cell visible at the hyphal tip. The neck of the swollen cell has become thin and the hyphal surface is smooth. Magnification 100×. Scale bar: 100 nm.