Figure 4: Histological images of skin tissues stained by hematoxylin and eosin after 7 (A-B, 20×) and 14 (C-D, 10×) days of treatment. A: The tissue section of the control group shows immature granulation tissue (IGT). B: The group treated with Acanthus leucostachyus extracts shows mature granulation tissue (MGT). C: The tissue section of the control group shows a thin epithelial layer (ET). D: The group treated with Acanthus leucostachyus shows a thicker epithelial layer compared to the control. Scale bar: 100 μm (A-B); 200 μm (C-D).