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  Indian J Med Microbiol
 

Figure 7: Anti-tumor effect of DET in HCT116 xenograft mouse model. Body weight (A) and tumor volume (B) of DET- and 5-fluorouracil (5-FU)-treated nude mice measured once a week over four weeks. 5-FU served as positive drug control. (C) Immunohistochemical images of apoptosis- and autophagy- related protein expressions (positive cells are stained brown). Bars = 50 μm and magnification = 400x. (D) Fold change of positively stained cells of immunohistochemical images of DET-treated mice compared to vehicle controls. Data are expressed as mean ± SE (n=6). *P<0.05 compared to the control.

Figure 7: Anti-tumor effect of DET in HCT116 xenograft mouse model. Body weight (A) and tumor volume (B) of DET- and 5-fluorouracil (5-FU)-treated nude mice measured once a week over four weeks. 5-FU served as positive drug control. (C) Immunohistochemical images of apoptosis- and autophagy- related protein expressions (positive cells are stained brown). Bars = 50 μm and magnification = 400x. (D) Fold change of positively stained cells of immunohistochemical images of DET-treated mice compared to vehicle controls. Data are expressed as mean ± SE (n=6). *P<0.05 compared to the control.