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  Indian J Med Microbiol
 

Figure 5: Involvement of ROS and the MAPK pathway in DET-induced apoptosis in HCT116 cells. Representative blots (A) and bar chart (B) of MAPK protein expressions in DET-treated cells at 6-24 h. Representative blots (C) and bar chart (D) of MAPK protein expressions in DET-treated cells after NAC treatment. Representative blots (E) and bar chart (F) of the expression of apoptosis-related proteins after MAPK inhibitors treatment. GAPDH was used as loading control. Data are expressed as mean ± SE from three separate experiments. *P<0.05 compared to the control. #P<0.05 compared to DET-treated group.

Figure 5: Involvement of ROS and the MAPK pathway in DET-induced apoptosis in HCT116 cells. Representative blots (A) and bar chart (B) of MAPK protein expressions in DET-treated cells at 6-24 h. Representative blots (C) and bar chart (D) of MAPK protein expressions in DET-treated cells after NAC treatment. Representative blots (E) and bar chart (F) of the expression of apoptosis-related proteins after MAPK inhibitors treatment. GAPDH was used as loading control. Data are expressed as mean ± SE from three separate experiments. *P<0.05 compared to the control. #P<0.05 compared to DET-treated group.