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  Indian J Med Microbiol
 

Figure 2: Representative liver histology of rats given different treatments for 10 d and after induction of hepatotoxicity with carbon tetrachloride (2 mL/200 g) on days 9-10. Liver sections were stained with hematoxylin-eosin (original magnification ×40). The result showed no pathological change in 10% Tween 80 group (A) while moderate centrilobular necrosis with macrovesicular fatty change was noted in 10% Tween 80 + CCl4 group (B). Mild centrilobular necrosis was found in sylimarin + CCl4 group (C), massive necrosis was present in PFO (0.1 mL/200 g) + CCl4 group (D), and mild hepatic necrosis was identified in PFO (1 mL/200 g) + CCl4 group (E). CCl4 = carbon tetrachloride and PFO = perilla fruit oil.

Figure 2: Representative liver histology of rats given different treatments for 10 d and after induction of hepatotoxicity with carbon tetrachloride (2 mL/200 g) on days 9-10. Liver sections were stained with hematoxylin-eosin (original magnification <i>×</i>40). The result showed no pathological change in 10<i>%</i> Tween 80 group (A) while moderate centrilobular necrosis with macrovesicular fatty change was noted in 10% Tween 80 + CCl<sub>4</sub> group (B). Mild centrilobular necrosis was found in sylimarin + CCl<sub>4</sub> group (C), massive necrosis was present in PFO (0.1 mL/200 g) + CCl<sub>4</sub> group (D), and mild hepatic necrosis was identified in PFO (1 mL/200 g) + CCl<sub>4</sub> group (E). CCl<sub>4</sub> = carbon tetrachloride and PFO = perilla fruit oil.