Figure 2: DAPI staining images of SPC212 cancer cells treated with atranorin at different concentrations. The control group (A) and the group treated with 3 μΜ of atranorin (B) are similar in terms of nucleus morphology. The nuclei in both groups have normal morphology (thick arrow). Atranorin at 160 (C), 200 (D), 250 (E) and 300 (F) μΜ disrupts nucleus morphology in a dose-dependent manner. The nuclei are smaller in volume and condensed (thin arrow). All pictures are taken at 40* magnification Scale bars are 50 μ™ in all figures.