Asian Pacific Journal of Tropical Biomedicine

ORIGINAL ARTICLE
Year
: 2019  |  Volume : 9  |  Issue : 5  |  Page : 204--208

Antibacterial activity and bioactive compounds of 50% hydroethanolic extract of Alpinia zerumbet (Pers.) B.L. Burtt & R.M. Sm.


Ratree Tavichakorntrakool1, Aroonlug Lulitanond1, Arunnee Sangka1, Seksit Sungkeeree1, Natthida Weerapreeyakul2 
1 Centre for Research and Development of Medical Diagnostic Laboratories; Department of Clinical Microbiology, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand
2 Division of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen, Thailand

Correspondence Address:
Natthida Weerapreeyakul
Division of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002
Thailand

Objective: To evaluate antibacterial activity and the bioactive compounds of 50% hydroethanolic extract of Alpinia zerumbet (A. zerumbet) rhizomes. Methods: Eight reference microbial strains including two Gram-positive bacteria [Staphylococcus aureus (ATCC 29213) and Enterococcus faecalis (ATCC 29212)] and six Gram-negative bacteria [Escherichia coli (ATCC 25922), Klebsiella pneumoniae (ATTC 700603), Proteus mirabilis (DMST 8212), Salmonella enterica subsp. enterica serovar Vellore. (ATCC 15611), Shigella flexneri (ATCC 12022) and Pseudomonas aeruginosa (ATCC 27853)], were used to test antimicrobial susceptibility by the broth microdilution method. Bioactive compounds were analyzed by using HPLC. Results: The minimum inhibitory concentration values of A. zerumbet extract were 8 mg/mL for Staphylococcus aureus, Escherichia coli and Shigella flexneri and 16 mg/mL for Enterococcus faecalis and the other four Gram-negative bacilli. HPLC chromatograms revealed that the A. zerumbet extract contained hydroxybenzoic acids, hydroxycinnamic acids and flavonoids. Conclusions: The constituents of A. zerumbet rhizomes could be a potential source of antibacterial compounds, warranting further study of A. zerumbet extract.


How to cite this article:
Tavichakorntrakool R, Lulitanond A, Sangka A, Sungkeeree S, Weerapreeyakul N. Antibacterial activity and bioactive compounds of 50% hydroethanolic extract of Alpinia zerumbet (Pers.) B.L. Burtt & R.M. Sm. Asian Pac J Trop Biomed 2019;9:204-208


How to cite this URL:
Tavichakorntrakool R, Lulitanond A, Sangka A, Sungkeeree S, Weerapreeyakul N. Antibacterial activity and bioactive compounds of 50% hydroethanolic extract of Alpinia zerumbet (Pers.) B.L. Burtt & R.M. Sm. Asian Pac J Trop Biomed [serial online] 2019 [cited 2022 Aug 13 ];9:204-208
Available from: https://www.apjtb.org/article.asp?issn=2221-1691;year=2019;volume=9;issue=5;spage=204;epage=208;aulast=Tavichakorntrakool;type=0