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REVIEW ARTICLE
Year : 2022  |  Volume : 12  |  Issue : 6  |  Page : 233-242

Prodigiosin from Serratia: Synthesis and potential applications


1 Laboratory of Molecular and Cellular Screening Processes, Centre of Biotechnology of Sfax, University of Sfax, PO box 1177, Road Sidi Mansour km 6, 3018 Sfax, Tunisia
2 Laboratory "Plant Biotechnology", Department of Biology, Faculty of Sciences, University Ibn Zohr, B.P 8106, 80000 Agadir, Morocco

Correspondence Address:
Sami Mnif
Laboratory of Molecular and Cellular Screening Processes, Centre of Biotechnology of Sfax, University of Sfax, PO box 1177, Road Sidi Mansour km 6, 3018 Sfax
Tunisia
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2221-1691.345515

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Prodigiosin is a red pigment with a pyrrolylpyrromethane skeleton. It is mainly produced by bacterial strains belonging to the Serratia genus, but also by some other genera, including Streptomyces and Vibrio. Within the genus Serratia, the pigment is generally produced as a virulence factor. However, it also has many important beneficial biological activities such as immunosuppressive and anti- proliferative activities. Moreover, the pigment has many industrial applications in textile and cosmetics. In this mini-review, we discuss the genetic and molecular mechanisms supporting prodigiosin synthesis and production from the Serratia genus, as well as its potential applications.


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