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REVIEW
Year : 2018  |  Volume : 8  |  Issue : 2  |  Page : 130-136

Diospyros lycioides Desf.: Review of its botany, medicinal uses, pharmacological activities and phytochemistry


Medicinal Plants and Economic Development Research Centre, Department of Botany, University of Fort Hare, Private Bag X1314, Alice 5700, South Africa

Correspondence Address:
Alfred Maroyi
Medicinal Plants and Economic Development Research Centre, Department of Botany, University of Fort Hare, Private Bag X1314, Alice 5700
South Africa
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2221-1691.225617

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Diospyros lycioides Desf. (D. lycioides) is traditionally used as herbal medicine against various human and animal ailments in tropical Africa. The present paper reviewed information on botany, medicinal uses, phytochemistry and pharmacological activities of D. lycioides. This review was compiled using scientific literature from electronic search engine such as PubMed, Scopus, ScienceDirect, Springerlink, BioMed Central, Scielo, Medline and Science domain. Additional literatures were obtained from book chapters, books, dissertations, websites and other scientific publications. D. lycioides is used as traditional medicine in 50% of the countries where the species is native in tropical Africa. This study recorded 22 medicinal uses of D. lycioides which included abdominal pains, infertility in women, sexually transmitted infections, and used as chewing sticks (or mouthwash), toothbrushes and ethnoveterinary medicine. D. lycioides extracts demonstrated anti-adhesive, anti-inflammatory, antimetastatic, antioxidant, antifungal, antiproliferative, mutagenicity and antibacterial activities. Future research should focus on the pharmacological properties, phytochemistry, clinical trials and pharmacokinetics of D. lycioides which will enhance the therapeutic potential of the species.


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